th mab5280 Search Results


th mab5280  (R&D Systems)
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R&D Systems th mab5280
Th Mab5280, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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monoclonal anti-th mab5280  (Millipore)
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Millipore monoclonal anti-th mab5280
Monoclonal Anti Th Mab5280, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse monoclonal antiserum th  (Millipore)
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Millipore mouse monoclonal antiserum th
Mouse Monoclonal Antiserum Th, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti-th  (Millipore)
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Millipore mouse anti-th
Mouse Anti Th, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti-th antibody mouse monoclonal mab52 80  (Millipore)
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Millipore anti-th antibody mouse monoclonal mab52 80
Anti Th Antibody Mouse Monoclonal Mab52 80, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti-th mab5280  (Merck KGaA)
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Merck KGaA anti-th mab5280
Anti Th Mab5280, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse monoclonal anti-th antibody clone 2/40/15  (Merck KGaA)
90
Merck KGaA mouse monoclonal anti-th antibody clone 2/40/15
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Mouse Monoclonal Anti Th Antibody Clone 2/40/15, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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monoclonal mouse anti-th antibody mab 5280  (Millipore)
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Millipore monoclonal mouse anti-th antibody mab 5280
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Monoclonal Mouse Anti Th Antibody Mab 5280, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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antibody peripherin mab1527  (Millipore)
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Millipore antibody peripherin mab1527
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Antibody Peripherin Mab1527, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti-th antibody  (Merck KGaA)
90
Merck KGaA mouse anti-th antibody
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Mouse Anti Th Antibody, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti-th  (Merck KGaA)
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Merck KGaA mouse anti-th
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Mouse Anti Th, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse th monoclonal antibody  (Millipore)
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Millipore mouse th monoclonal antibody
A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained <t>with</t> <t>anti-TH</t> antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.
Mouse Th Monoclonal Antibody, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained with anti-TH antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.

Journal: Cell Death & Disease

Article Title: ZSCAN21 mediates the pathogenic transcriptional induction of α-synuclein in cellular and animal models of Parkinson’s disease

doi: 10.1038/s41419-025-07722-w

Figure Lengend Snippet: A AAV vectors expressing control shRNAs (sh-Luc and sh-eGFP) or shRNAs against Trim17 (sh-T17) and Zscan21 (sh-Z21) were unilaterally injected in the midbrain of mice. Four weeks after injection, the mRNA levels of Trim17 and Zscan21 were measured both in the contralateral and ipsilateral midbrains of each mouse by RT-qPCR using β2-microglobulin and Hmbs as reference genes. Ipsilateral/contralateral mRNA ratios are presented as box plots, with minimum, maximum and median indicated. * Significant difference (one-way ANOVA followed by Sidak’s multiple comparison test). B Four weeks after injection of AAV vectors as in A, mice were subjected to or not (saline) to subacute MPTP treatment and were sacrificed three weeks after the last MPTP injection. Brain sections were stained with anti-TH antibody by immunohistochemistry, and representative images of the ipsilateral SN in the different conditions are shown. The scale bar is 200 μm. C The total number of TH-positive neurons in the SNpc of mice was counted by stereology in the different conditions. # Significantly different from control mice (saline) injected with the same AAV (two-way ANOVA followed by Sidak’s multiple comparison test); * Significantly different from sh-eGFP in the MPTP condition (two-way ANOVA followed by Dunnett’s multiple comparison test). NB: differences are also significant when compared with sh-Luc; in saline conditions, only shT17 is different from sh-Luc or sh-eGFP. D Some brain sections from the same mice analysed in B were used for a double immunofluorescence staining of TH and GFP. Representative pictures of the ipsilateral SNpc of MPTP-treated mice are shown. For each mouse, the decrease of the total number of TH-positive neurons in the SNpc, compared to the mean of control mice (saline) injected with the same shRNA, is indicated in white. NB: in mice exhibiting a strong MPTP-induced neurodegeneration, GFP is not expressed in the SNpc, whereas in mice showing a strong neuroprotection, GFP expression is strong in the SNpc.

Article Snippet: Mouse monoclonal anti-TH antibody (clone 2/40/15, #MAB5280) and mouse monoclonal anti-actin antibody (clone C4, #MAB1501) were from Merck Millipore.

Techniques: Expressing, Control, Injection, Quantitative RT-PCR, Comparison, Saline, Staining, Immunohistochemistry, Double Immunofluorescence Staining, shRNA